Cocaine/levamisole-induced systemic vasculitis with retiform purpura and pauci-immune glomerulonephritis
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منابع مشابه
Cocaine/levamisole-induced systemic vasculitis with retiform purpura and pauci-immune glomerulonephritis.
Levamisole has been increasingly used as an adulterant of cocaine in recent years, emerging as a public health challenge worldwide. Levamisole-associated toxicity manifests clinically as a systemic vasculitis, consisting of cutaneous, hematological, and renal lesions, among others. Purpura retiform, cutaneous necrosis, intravascular thrombosis, neutropenia, and less commonly crescentic nephriti...
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'Pauci-immune' glomerulonephritis has been recognized as an important cause of rapidly progressive glomerulonephritis. The paucity of immune deposits can be separated from the other two major immunohistologic variants of crescentic glomerulonephritis, ie, antiglomerular basement membrane (GBM) antibody-mediated and immune complex-mediated glomerulonephritis. Here we describe the case of a 42-ye...
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متن کاملLevamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis
Levamisole is an antihelminthic and immunomodulator medication that was banned by the USFDA in 1998. It has been increasingly used to adulterate cocaine due to its psychotropic effects and morphological properties. Adverse reactions including cutaneous vasculitis, thrombocytopenia, and agranulocytosis have been well described. Despite systemic vasculitis in this setting, renal involvement is un...
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ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 2016
ISSN: 1414-431X,0100-879X
DOI: 10.1590/1414-431x20165244